Can someone tell me if Lipozene, a dietary supplement marketed for weight loss works? I heard there is simply no good evidence that the small doses of glucomannan offered by Lipozene could lead to significant weight loss. But, I have seen ads that claim that Lipozene’s fat-reducing power was "clinically proven" in a "recent major university double-blind study." Fine print at the bottom of the screen says that subjects lost an average of 3.86 pounds over eight weeks.